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Introducing PowerWire® Pro RF Guidewire

Safely cross native and in-stent occlusions using radiofrequency puncture technology

In the USA, PowerWire® Pro RF Guidewire is indicated to create a channel in totally occluded peripheral vessels 3 mm or greater, including vessels with stents.

In Canada, PowerWire® Pro RF Guidewire is indicated for creating a channel in totally occlusive peripheral vascular disease, in either native or previously stented vessels, for enhancing the potential for limb preservation.

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Cross chronic venous occlusions

When a standard guidewire fails, channel through using the PowerWire® Pro RF Guidewire

Overcome barriers to venous access

Up to 24%

CVOs Resistant to Standard techniques

Up to 24% of occlusions cannot be crossed with conventional recanalization techniques,1 leading to either prolongation or worsening of patient symptoms.2-4 These refractory cases present a formidable challenge to endovascular interventionalists & prevent patients from receiving the treatment they need.1-2

Witness the transformation

84%

Success rate with PowerWire® Pro RF Guidewire

In the face of 100% failure with standard tools, PowerWire® Pro RF Guidewire achieved an 84% success rate, ensuring patients receive the crucial treatments they need.1-13

Witness the transformation

84%

Success rate with PowerWire® Pro RF Guidewire

In the face of 100% failure with standard tools, PowerWire® Pro RF Guidewire achieved an 84% success rate, ensuring patients receive the crucial treatments they need.1-13

Safely cross occlusions using RF Puncture Technology

RF Puncture Technology

Creates a small opening in tissue with minimal damage to surrounding area
High impedance High voltage Short RF delivery time
Low power Small active tip

How does RF puncture differ from RF ablation?

Ordering Information

Product Code Tip Strength Tip Shape
PSK35-250-10-6S
75 g
Straight
PSK35-250-12-6S
110 g
Straight
PSK35-250-12-6A-20
110 g
Angled 20°
PSK35-250-12-6A-30
110 g
Angled 30°

PSK35-250-12-6A-40

110 g

Angled 40°

PowerWire® Pro RF Guidewire Clinical Compendium

Learn how to cross complete
venous occlusions with the Sniper Technique

This four-part educational series, equips endovascular interventionalists with advanced techniques for successful venous recanalization. Review all facets of the Sniper Technique, from pre-procedural planning to post-operative care, to facilitate safe and effective recanalization of even the most complex central venous occlusions (CVOs) and iliac vein obstructions.

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Play Video

Part 1: Patient Selection and Pre-Procedural Planning

Review critical anatomy and imaging when planning for the Sniper Technique. Explore advanced imaging techniques that can be implemented to enhance procedural efficiency and safety.

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Play Video

Part 2: Tools and Room Preparation

Review tools, equipment, and room setup to facilitate a successful procedure.

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Play Video

Part 3: Recanalization of Challenging Central Venous Occlusions (CVOs)

Explore the step-by-step technique for radiofrequency (RF)-assisted crossing of CVOs with the PowerWire® RF Guidewire (“RF Wire”).

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Play Video

Part 4: Addressing Complex Lower Extremity Occlusions

Review advanced techniques when approaching challenging lower extremity venous occlusions for safe and effective intervention.

Resource Library

Browse content specific to this product, such as brochures, publications, white papers, IFUs, videos and other product information.

Powerwire Pro Brochure
Powerwire Pro IFU
Powerwire Pro IFU
Powerwire Pro IFU
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Clinical Case Support

We provide product training, clinical support, and ongoing communication to interventionalists and their support teams to ensure optimal utilization of our technologies.

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References:
  1. Guimaraes, M., Schonholz, C., Hannegan, C., Anderson, M. B., Shi, J., & Selby, B., Jr. (2012). Radiofrequency wire for the recanalization of central vein occlusions that have failed conventional endovascular techniques . J Vasc Interv Radiol, 23(8), 1016-1021. https://doi.org/10.1016/j.jvir.2012.05.049
  2. Keller, E. J., Gupta, S. A., Bondarev, S., Sato, K. T., Vogelzang, R. L., & Resnick, S. A. (2018). Single-Center Retrospective Review of Radiofrequency Wire Recanalization of Refractory Central Venous Occlusions . J Vasc Interv Radiol, 29(11), 1571-1577. https://doi.org/10.1016/j.jvir.2018.06.017
  3. Iafrati, M., Maloney, S., & Halin, N. (2012). Radiofrequency thermal wire is a useful adjunct to treat chronic central venous occlusions [Duplicate]. J Vasc Surg, 55(2), 603-606. https://doi.org/10.1016/j.jvs.2011.09.090
  4. Kundu, S., Modabber, M., You, J. M., & Tam, P. (2012). Recanalization of chronic refractory central venous occlusions utilizing a radiofrequency guidewire perforation technique . J Vasc Access, 13(4), 464-467. https://doi.org/10.5301/jva.5000087
  5. Foley, P. W. X., & Chandrasekaran, B. (2023). Radiofrequency thermal wire for crossing subclavian vein occlusion allows lead upgrade in patient with pre-existing transvenous device. HeartRhythm Case Reports, 9(5), 304–305. https://doi.org/10.1016/j.hrcr.2023.02.006

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References:

  1. Guimaraes, M., Schonholz, C., Hannegan, C., Anderson, M. B., Shi, J., & Selby, B., Jr. (2012). Radiofrequency wire for the recanalization of central vein occlusions that have failed conventional endovascular techniques . J Vasc Interv Radiol, 23(8), 1016-1021. https://doi.org/10.1016/j.jvir.2012.05.049
  2. Keller, E. J., Gupta, S. A., Bondarev, S., Sato, K. T., Vogelzang, R. L., & Resnick, S. A. (2018). Single-Center Retrospective Review of Radiofrequency Wire Recanalization of Refractory Central Venous Occlusions . J Vasc Interv Radiol, 29(11), 1571-1577. https://doi.org/10.1016/j.jvir.2018.06.017
  3. Iafrati, M., Maloney, S., & Halin, N. (2012). Radiofrequency thermal wire is a useful adjunct to treat chronic central venous occlusions [Duplicate]. J Vasc Surg, 55(2), 603-606. https://doi.org/10.1016/j.jvs.2011.09.090
  4. Kundu, S., Modabber, M., You, J. M., & Tam, P. (2012). Recanalization of chronic refractory central venous occlusions utilizing a radiofrequency guidewire perforation technique . J Vasc Access, 13(4), 464-467. https://doi.org/10.5301/jva.5000087
  5. Foley, P. W. X., & Chandrasekaran, B. (2023). Radiofrequency thermal wire for crossing subclavian vein occlusion allows lead upgrade in patient with pre-existing transvenous device. HeartRhythm Case Reports, 9(5), 304–305. https://doi.org/10.1016/j.hrcr.2023.02.006
  6. Patel, R., Ahuja, A., & Resnick, S. (2021). Percutaneous retrieval of a Mobin-Uddin inferior vena cava filter 42 years following implantation. Diagnostic and interventional radiology (Ankara, Turkey), 27(6), 792–795. https://doi.org/10.5152/dir.2021.20984
  7. Salaskar, A., Ferra, M., Narayanan, H. et al. Radiofrequency wire ‘power wire’ recanalization of calcified chronically occluded inferior vena cava. CVIR Endovasc 1, 24 (2018). https://doi.org/10.1186/s42155-018-0030-4
  8. Sivananthan, G., MacArthur, D. H., Daly, K. P., Allen, D. W., Hakham, S., & Halin, N. J. (2015). Safety and efficacy of radiofrequency wire recanalization of chronic central venous occlusions. J Vasc Access, 16(4), 309-314. https://doi.org/10.5301/jva.5000360
  9. Tapping, C. R., Uri, I. F., Dixon, S., Bratby, M. J., Anthony, S., & Uberoi, R. (2012). Successful recanalization of a longstanding right common iliac artery occlusion with a radiofrequency guidewire . Cardiovasc Intervent Radiol, 35(5), 1221-1225. https://doi.org/10.1007/s00270-011-0327-3
  10. Tingerides, C., Annamalai, G., Comin, J. M., Kaduri, S., Pugash, R., & David, E. (2016). Percutaneous Recanalization of Iliac Artery Occlusions by Radiofrequency Perforation: Initial Experience. J Vasc Interv Radiol, 27(1), 68-72. https://doi.org/10.1016/j.jvir.2015.09.019
  11. Yee N, D. J. (2014). Extravascular Reconstruction of a Chronic Central Venous Occlusion. ENDOVASCULAR TODAY
  12. Majdalany, B. S., Monfore, N., Khaja, M. S., & Williams, D. M. (2018). Radiofrequency wire recanalization of chronically occluded venous stents: A retrospective, single-center experience in 15 patients. CardioVascular and Interventional Radiology, 42(1), 130–136. https://doi.org/10.1007/s00270-018-2076-z
  13. Shapiro, J. N., Neville, E., Robertson, B., Rucker, L. G., Fellner, A. N., Kuhn, B. F., Recht, M., Kulwicki, A., Broering, M., & Muck, P. (2022). Novel therapy for recanalization of chronic iliocaval venous occlusion using radiofrequency. Journal of Vascular Surgery: Venous and Lymphatic Disorders, 10(6), 1288–1293. https://doi.org/10.1016/j.jvsv.2022.07.005
  14. Clark TWI., Moawad, S., Vance, A.Z., Cobb, R.M. et al. Radiofrequency guidewire-facilitated recanalization of chronic thoracic central venous occlusions in hemodialysis patients. CVIR Endovasc 7, 10 (2024). https://doi.org/10.1186/s42155-023-00422-6
  15. Neidert, N. B., & Bjarnason, H. (2019). Effectiveness of the PowerWire Radiofrequency Guidewire in recanalizing chronically occluded iliac venous stents. Journal of Vascular Surgery. Venous and Lymphatic Disorders, 7(2), 299–300. https://doi.org/10.1016/j.jvsv.2019.01.033
  16. Tavallaei, M. A., Zhou, J. J., Roy, T. L., & Wright, G. A. (2018). Performance Assessment of a Radiofrequency Powered Guidewire for Crossing Peripheral Arterial Occlusions Based on Lesion Morphology . Ann Biomed Eng, 46(7), 940-946. https://doi.org/10.1007/s10439-018-2021-y

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Products shown may not be approved or available in all jurisdictions. Indications, claims, and clinical content may vary based on regional regulatory requirements. Please consult the product labeling and Instructions for Use for applicable regional information.

Maximum Outer Diameter

Handles like a conventional 0.035″ guidewire. Allows for use with third party, over the wire devices such as venous thrombectomy devices.

Length

Allows for use with third party, over the wire devices such as venous thrombectomy devices.

Tip Strength

Increasing tip strength corresponds to increasing stiffness.

Safe Crossing Technology

Contact with metal terminates RF energy, reducing the potential for vessel extravasation when crossing in-stent occlusions.

Tip Shapes

Straight

Angled 20°

Angled 30°

Angled 40°

Visibility

Radiopaque tip and five radiopaque marker bands (1 cm apart) for visibility under fluoroscopy. Visualize the radiopaque tip within the stent under fluoroscopy.

RF puncture creates a small opening in tissue with minimal surrounding tissue damage. RF Ablation creates a large lesion to destroy electrically conductive tissue. RF Ablation uses:
   Low impedance    Low voltage    Longer RF delivery time
   High power    Large active tip
The PowerWire® Pro RF Guidewire enables reliable and repeatable vascular recanalization for both native and stented vessel occlusions unresponsive to traditional techniques. The PowerWire® Pro RF Guidewire can successfully cross occlusions that have previously failed mechanical recanalization attempts in 125/149 (84%) of reported cases, 95/111 (86%) of native vessels, and 30/38 (79%) of stented vessels.
The PowerWire® Pro RF Guidewire is a versatile tool that has been shown to effectively recanalize lesions found in several areas of the vasculature in both native and stented blood vessels. Investigators have successfully recanalized lesions of the left brachiocephalic vein, a notably difficult anatomy to traverse due to its tortuosity.

PowerWire® Pro RF Guidewire enables the restoration of hemodialysis access, which alleviates symptoms associated with vascular occlusions. Hemodialysis access was restored and symptoms such as swollen arms and superior vena cava syndrome were resolved in published cases where the PowerWire® Pro RF guidewire was used to recanalize the underlying lesion causing these symptoms.

Reported Symptoms Resolved Following Successful Recanalization Article
Pain and Swelling (arm, face, neck, axillary, extremities) [4] Guimaraes et al.
[2] Clark et al.
[6] Iafrati et al.
[8] Kundu et al.
[7] Keller et al.
[15] Yee et al.
Face, leg, and chest edema [7] Keller et al.
[11] Sivananthan et al.
Loss of dialysis access or access dysfunction with decreased access flows measuring less than 650 mL/min [7] Keller et al.
[8] Kundu et al.
Claudication symptoms [14] Tingerides et al.
[12] Tapping et al.
Headache [6] Iafrati et al.
Use of the PowerWire® Pro RF Guidewire requires minimal force to cross an occlusive lesion when compared to use of a traditional guidewire.

New Clinical Compendium on the PowerWire® Pro RF Wire